Amid increasing attention for GLP-1 RAs, a panel of experts summarized a broad spectrum of topics related to these medications, including emerging pharmacological options, muscle physiology, obesity treatment for osteoarthritis, and nutritional counseling.
Mohammed K. Ali, MD, MSc, MBA, who was being honored for his contributions to diabetes epidemiology, said the field is poised to move beyond a “one-size-fits-all” approach to diabetes public health policies.
Matthias H. Tschöp, MD, and other researchers detailed phase 3 results of SYNCHRONIZE-1 and SYNCHRONIZE-MASLD showing that survodutide leads to significant weight loss, reduction in liver fat, and other health improvements.
Donna Ryan, MD, and other panelists reported on new data from phase 3 trials evaluating the combination of cagrilintide, which mimics amylin, and semaglutide, a glucagon-like peptide-1 receptor agonist, in adults.
Trevor Reichman, MD, moderated the discussion, which included insights into eligibility criteria, immunosuppression, regulatory concerns, and top priorities.
Sherita Hill Golden, MD, MHS, and other presenters examined what needs to be done in diabetes care to better understand and provide treatment for the nation’s increasingly racially and ethnically diverse populations living with the disease.
Leaders of three start-up ventures pitched their novel product ideas at the Scientific Sessions and exited with connections for opportunities to accelerate their visions for redefining diabetes care and treatment.
A. Enrique Caballero, MD, highlighted the progress advancing diabetes treatment and management while shedding light on existing gaps in care and advocating for integrating advances in science into the real-world context in which people live.
In his award lecture, Takashi Kadowaki, MD, PhD, explained how contradictions between hypotheses and results have enabled him to achieve major breakthroughs in understanding type 2 diabetes.
Activation of the glucagon receptor with retatrutide is being investigated in a large phase 3 program that includes 14 trials and more than 22,000 participants. Researchers, including Ania Jastreboff, MD, PhD, shared data from two of the trials, TRANSCEND-T2D-1 and TRIUMPH-1.