Deborah Horn, DO, MPH, MFOMA, Pam R. Taub, MD, FACC, FASPC, and Neda Rasouli, MD, offered different perspectives on which patients should receive priority when determining access to glucagon-like peptide-1 (GLP-1) receptor agonists.
Panelists discussed novel insulin-dependent and insulin-independent mechanisms of glucose transport into skeletal muscles. Katrin Svensson, PhD, showed that the protein isthmin-1, which is secreted by adipose cells, has some of the same activities as insulin.
Rury R. Holman, MBChB, FRCP(Lond), FMedSci, co-led the UKPDS trial, which found that progressive hyperglycemia is a key feature of type 2 diabetes driven by the declining function of beta-cells, as opposed to insulin resistance.
Stephen C.J. Parker, PhD, likened his work to assembling LEGO bricks. Simple parts are assembled to form complex structures that do not resemble the components in form or function.
V. Mohan, MD, PhD, DSc, FRCP, FNA, FACE, MACP, FRSE, highlighted the increase in type 2 diabetes among Asian Indians, concomitant with the socioeconomic growth fostered by the liberalization and globalization of India.
Two trials of semaglutide show similar improvement in heart failure symptoms and weight loss in patients with BMI >30 who have heart failure with preserved ejection fraction with or without diabetes, reported Mikhail N. Kosiborod, MD, and other investigators.
A diverse lineup of experts including John-Michael Gamble, PhD, took a deep dive into the data on known and potential severe adverse effects of glucagon-like peptide-1 (GLP-1) receptor agonists.
Loneliness and social isolation are related but different. Anne Gaglioti, MD, MS, FAAFP, and other panelists discussed loneliness, its link to diabetes, and the psychological toll it takes on patients living with diabetes.
A diagnosis of post-transplant diabetes (PTDM) can directly affect the patient’s outcome. Archana R. Sadhu, MD, FACE, and other experts discussed the pathophysiology and patient management of PTDM.
Members of the new Diabetes Primary Care Alliance came together to discuss opportunities to improve diabetes outcomes by accelerating the adoption of evidence-based standards of care in primary care.