2024 Presenter Profiles
Omics to Understand Genome-Wide Association Study—What’s the Mechanism?
Monday, June 24, at 8:00 a.m. ET
Room W207
Orange County Convention Center
Genome-Wide Association Study Functional Follow-up at a Single Locus
Nicole Krentz, PhD
Assistant Professor,
University of British Columbia
What is your presentation about?
Genome-wide association studies have identified over 1,200 independent association signals with type 2 diabetes. Each of these signals represents an opportunity to better understand the pathophysiology of diabetes. In my presentation, I will discuss our collaborative efforts to perform functional follow-up studies at a single locus.
How do you hope your presentation will impact diabetes research or care?
There is a strong genetic contribution to the development of type 2 diabetes. Studies such as ours help improve our understanding of the genetics of type 2 diabetes, which may lead to more targeted drug treatments in the future.
How did you become involved with this area of diabetes research or care?
I first became involved with the genetics of type 2 diabetes during my postdoctoral fellowship. I am particularly interested in using human genetics to identify new cellular and molecular mechanisms of diabetes pathogenesis.
