With its powerful algorithm in every Pod, the Omnipod 5 Automated Insulin Delivery (AID) System delivers improved glycemic results,1-3 a tube-free lifestyle, and the features patients want – all in a waterproof system that users agree is easy to use.*,4
Omnipod 5 real-world evidence demonstrated that type 1 and type 2 patients achieved over 80% time in range (TIR) with optimized settings.5 Find out how and discover the advantages of Omnipod 5, the #1 patient-requested and #1 prescribed AID system in the U.S.6,7
5. Retrospective RWE data on file. 2025. Results shown for users with optimized settings including sufficient CGM data (≥75% of days with ≥220 readings), ≥90% time in Automated Mode, ≥5 bolus/day and an average Target Glucose of 110-115 mg/dL (6.1-6.4 mmol/L). Optimized settings: ISF x TDI ≤1500, I:C Ratio x TDI ≤350. RF-062025-00014
From Standards to Success: Bridging the Gap with Omnipod 5
ADA Standards state AID is now the preferred insulin delivery method (over MDI, continuous subcutaneous insulin infusion and sensor-augmented pumps).8
Help your type 1 diabetes patients over the age of 2 years, and adults 18+ with type 2 diabetes transition to the Omnipod 5 AID System for simplified diabetes management, outstanding clinical results, and accessible coverage available through the pharmacy. Over 90% insured patients nationwide are covered for Omnipod 5.9
Clinical Results Across T1D and T2D
Switching to Omnipod 5 From MDI Boosts TIR for T1D Patients
– The RADIANT Randomized Controlled Trial showed improved TIR by an average of 23% for T1D adults and 20% for children and adolescents with T1D, compared with MDI users10
Improved Results for People with T2 Diabetes on Omnipod 5
– The SECURE T2D study showed a 2.1% decrease in A1C for people living with type 2 diabetes with a baseline A1C ≥9%, without increasing hypoglycemia3
Strong Results Start with Strong Settings
53% of Omnipod 5 users not achieving glycemic targets do not frequently use the lowest Target Glucose setting of 110 mg/dL.11 Get real-world insights and the optimized settings to maximize TIR for your Omnipod 5 patients.
See what’s next for Omnipod at Booth #1918
Omnipod 5 is indicated for people with type 1 diabetes, ages 2 years and older and type 2 diabetes in persons 18 years of age and older. Rx only. WARNING: Do not use SmartAdjust™ technology for people under the age of 2 or who require less than 5 U of insulin per day. Please see omnipod.com/safety for important safety information.
*The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Controller is not waterproof.
**Only available for users with valid prescription and coverage through their pharmacy benefit. Exact coverage depends on patient’s insurance plan. Upgrades subject to user’s insurance coverage.
- Brown S, et al. Diabetes Care. 2021;44:1630-1640. Prospective pivotal trial in 240 participants with T1D aged 6-70 yrs [adults/adolescents (n= 128; aged 14-70 yrs) children (n=112; aged 6-13.9 yrs)]. Study included a 14-day standard therapy (ST) phase followed by a 3-month Omnipod 5 hybrid closed-loop phase. Mean time 70-180 mg/dL as measured by CGM in adults/adolescents and children, ST vs. 3-month Omnipod 5: 64.7% vs. 73.9%; 52.5% vs. 68.0%, P<0.0001, respectively.
- Sherr JL, et al. 2022. 45(8):1907–1910. Prospective trial in 80 participants with T1D aged 2-5.9 yrs. Study included a 14-day standard therapy (ST) phase followed by a 3-month Omnipod 5 hybrid closed-loop (HCL) phase. Mean time in range (70-180mg/dL) in very young children (2-5.9 yrs) as measured by CGM: ST = 57.2%, 3-month Omnipod 5 = 68.1%, P<0.05.
- Pasquel FJ, et al. JAMA Network Open (2025). Prospective pivotal trial in 305 participants with T2D aged 18-75 yrs. Study included a 14-day standard therapy (ST) phase followed by a 13-week Omnipod 5 hybrid closed-loop phase. Mean time in range (70-180 mg/dL): ST vs. 13-week Omnipod 5: 45% vs. 66%, P<0.001. Mean time <70 mg/dL as measured by CGM: ST = 0.2%, 3-month Omnipod 5 = 0.2%. In a subgroup analysis of 68 participants with baseline A1c ≥ 9% Mean HbA1c: ST vs. 13-week Omnipod 5: 10.1% vs. 8.1%; (95% CI: -2.3%, -1.9%).
- Insulet Data on File. OP5-003 Clinical Study Report. 2024.13-week randomized, parallel-group clinical trial conducted among 194 adults (age 18-70) with type 1 diabetes in France and the U.S., comparing the safety and effectiveness of the Omnipod 5 System versus pump therapy with CGM.
- Retrospective RWE data on file. 2025. Results shown for users with optimized settings including sufficient CGM data (≥75% of days with ≥220 readings), ≥90% time in Automated Mode, ≥5 bolus/day and an average Target Glucose of 110-115 mg/dL (6.1-6.4 mmol/L). Optimized settings: ISF x TDI ≤1500, I:C Ratio x TDI ≤350. RF-062025-00014
- 2025, Data on file
- Omnipod was the pump most frequently requested by people with type 1 and type 2 diabetes in a survey with Endocrinologists conducted by dQ&A across the United States. n=77 (T1) and n=63 (T2); H2 2024; P.25.
- American Diabetes Association Professional Practice Committee for Diabetes. 7. Diabetes technology: Standards of Care in Diabetes—2026. Diabetes Care 2026;49(Suppl. 1): S150–S165
- Reflects coverage for Omnipod 5 DexG7G6 Intro Kit and Omnipod 5 DexG7G6 Pods in commercial channel only. Majority defined as >50%. Source: Managed Markets Insights & Technology, LLC. Data as of April 2025.
- Wilmot E, et al. Lancet (2026) A 13-week randomized, parallel-group clinical trial conducted among 188 participants (age 4-70) with type 1 diabetes in France, Belgium, and the U.K., comparing the safety and effectiveness of the Omnipod 5 System versus multiple daily injections with CGM. TBR (<70 mg/dL) at 13-weeks: non-inferiority was met with 2.56% TBR with Omnipod 5. Data on File. 2025. RF-042025-00020 & RF-052025-00033
- Insulet data on file. 2025. Retrospective analysis including 103,369 T1D users with TIR (3.9-10.0 mmol/L or 70-180 mg/dL) <70%. 54,365 (53%) did not use the 110mg/dL (6.1mmol/L) target as their average glucose target setting. RF-062025-00038
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